Paediatric Active Enhanced Disease Surveillance (PAEDS) is a system to identify conditions of public health importance in children with particular focus on vaccine preventable diseases.
In addition to operating at Perth Children’s Hospital, PAEDS operates at multiple other large children’s hospitals across Australia. The information collected is used to help identify and monitor specific paediatric conditions in children who are unwell enough to come to hospital. It also assists researchers in understanding what factors put children at risk of developing certain diseases and to monitor the effectiveness and safety of vaccination.
PAEDS investigates many conditions including acute flaccid paralysis (sudden onset of limb weakness), encephalitis (inflammation of the brain), influenza, intussusception (a form of bowel obstruction), pertussis (whooping cough), varicella zoster virus infection (chicken pox and shingles), meningococcal disease and group A streptococcus (serious bacterial infection).
New diseases we’ve added this year include Kawasaki Disease (KD) and Gram-negative bloodstream infection (GNBSI). KD is a relatively common vasculitic disease of childhood of which the underlying cause remains elusive. The disease presents with a constellation of non-specific signs and symptoms such as a fever accompanied by rash, but in some children it can progress to involve the heart. This study is designed to gain insight into physician attitudes towards diagnosis and management and to construct the clearest picture of KD epidemiology, diagnosis and management in Australia.
Gram-negative bloodstream infection (GNBSI) presents a particular concern as evidence emerges of increasing rates of antimicrobial resistance and rates of severe infections in children requiring intensive care support. This study will focus on collecting data to describe the epidemiology of bloodstream infection of children in Australia.